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Cardiomyocytes close to the left ventricular endocardium showed higher CPT1B protein levels than cardiomyocytes in the inner field

Further expansion seems likely with the Food and Drug Administrations recent approval of another class of medications to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and either obesity or overweight

Its small size confers favorable physicochemical properties for solubility, stability, and intranasal or subcutaneous delivery, but also raises questions about specificity that are common to short peptides in vivo proteolytic stability, off-target binding, and minimum receptor recognition motif identification all require additional characterization that the published literature does not yet fully provide

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